THE COLLAGEN-BASED MEDICAL DEVICE MD-TISSUE ACTS AS A MECHANICAL SCAFFOLD INFLUENCING MORPHO-FUNCTIONAL PROPERTIES OF CULTURED HUMAN TENOCYTES

The Collagen-Based Medical Device MD-Tissue Acts as a Mechanical Scaffold Influencing Morpho-Functional Properties of Cultured Human Tenocytes

Mechanotransduction is the ability of cells to translate mechanical stimuli into biochemical signals that can ultimately influence gene expression, cell morphology and cell fate.Tenocytes are responsible for tendon mechanical adaptation converting mechanical stimuli imposed during mechanical loading, thus affecting extracellular matrix homeostasis.

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Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats

Abstract Background Nucleus Accumbens (NAc) is a vital brain region for the process of reward and stress, whereas microRNA plays a crucial role in depression pathology.However, the abnormality of NAc miRNA expression during the stress-induced depression and antidepressant treatment, as well as its biological significance, are still unknown.Methods

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Small Bowel Malignancy in Patient with Obscure Gastrointestinal Bleeding in Cipto Mangunkusumo Hospital, Diagnosed Using Double Balloon Enteroscopy: A Case Series

Small bowel malignancy is still a rare case as a cause top bar mega of gastrointestinal bleeding.The symptoms of small bowel malignancy are not specific.One of the symptoms is obscure gastrointestinal bleeding.Obscure gastrointestinal bleeding (OGIB) is defined as recurrent or persistent gastrointestinal bleeding when the result esophagogastroduode

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